Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939135 | 0.81 | ALDH1A1 (0.40) | ACHEL3MBTL1CA1CA2CA7 | |
| SCHEMBL14938952 | 0.79 | CDK5 (0.40) | L3MBTL1CA1CA2CA7CA9 | |
| SCHEMBL14939641 | 0.78 | MAPT (0.34) | MAPTTP53KDM4EKMT2ARAB9A | |
| SCHEMBL14938950 | 0.78 | SRD5A1 (0.36) | CA1CA2CA7CA9MAPT | |
| SCHEMBL14939748 | 0.77 | CA1 (0.43) | ACHEL3MBTL1CA1CA2CA7 | |
| SCHEMBL10624432 | 0.75 | L3MBTL1 (0.55) | ACHEL3MBTL1CA1CA2UGCG | |
| SCHEMBL18071522 | 0.74 | ACHE (0.49) | ACHEL3MBTL1CA1CA2UGCG | |
| SCHEMBL15692838 | 0.74 | ACHE (0.49) | ACHEL3MBTL1CA1CA2UGCG | |
| SCHEMBL15692861 | 0.72 | ACHE (0.46) | ACHEL3MBTL1CA1CA2UGCG | |
| SCHEMBL15692718 | 0.72 | ACHE (0.46) | ACHEL3MBTL1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |