Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940606 | 0.81 | MAPT (0.39) | KMT2AGFERLMNAALDH1A1MAPT | |
| SCHEMBL2477886 | 0.73 | ALDH1A1 (0.47) | KMT2AGAALMNAALDH1A1MAPT | |
| SCHEMBL14940517 | 0.72 | ALDH1A1 (0.46) | KMT2AGAAMEN1LMNAALDH1A1 | |
| SCHEMBL2479088 | 0.72 | KDM4E (0.39) | KMT2AGAAMEN1LMNAALDH1A1 | |
| SCHEMBL2479695 | 0.70 | PDE10A (0.34) | KMT2AGAAMEN1LMNAALDH1A1 | |
| SCHEMBL2477801 | 0.70 | SMPD3 (0.42) | KDM4EAR | |
| SCHEMBL2885764 | 0.69 | PDE4A (0.44) | LMNAALDH1A1MAPT | |
| SCHEMBL3699278 | 0.69 | ALDH1A1 (0.35) | KMT2AGAAGFERMEN1ALDH1A1 | |
| SCHEMBL188354 | 0.68 | DRD2 (0.60) | KMT2AGAAMEN1LMNAHRH3 | |
| SCHEMBL283083 | 0.67 | DRD2 (0.47) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068592-A1 | INHIBITORS OF CYSTATHIONINE BETA SYNTHASE TO REDUCE THE NEUROTOXIC OVERPRODUCTION OF ENDOGENOUS HYDROGEN SULFIDE | FONDATION JEROME LEJEUNE (FR) | 2013-05-16 | — | — | WO | disclosed |