Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13032088 | 0.93 | CA2 (0.35) | CA2FBP1PIK3CDPIP5K1CPIK3CB | |
| SCHEMBL14943017 | 0.87 | CLK1 (0.34) | LMNACLK1CA2SCDKAT6A | |
| SCHEMBL13032085 | 0.79 | CA2 (0.33) | CA2 | |
| SCHEMBL14943032 | 0.78 | TRPV4 (0.37) | KAT6A | |
| SCHEMBL14943013 | 0.76 | AR (0.36) | CLK1 | |
| SCHEMBL3483784 | 0.75 | CA2 (0.38) | CLK1CA2FBP1 | |
| SCHEMBL3483435 | 0.74 | CA2 (0.34) | CA2FBP1PIK3CDPIP5K1CPIK3CB | |
| SCHEMBL16667354 | 0.74 | TBXAS1 (0.31) | CA2 | |
| SCHEMBL3483790 | 0.74 | CA2 (0.38) | CLK1CA2FBP1 | |
| SCHEMBL3483211 | 0.74 | CA2 (0.38) | CA2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | disclosed |