Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13032085 | 0.92 | CA2 (0.33) | CA2SLC40A1 | |
| SCHEMBL14943016 | 0.87 | LMNA (0.35) | CLK1LMNAKAT6ACA2SCD | |
| SCHEMBL14943032 | 0.84 | TRPV4 (0.37) | KAT6A | |
| SCHEMBL14942987 | 0.83 | CA2 (0.31) | CA2 | |
| SCHEMBL14943013 | 0.82 | AR (0.36) | CLK1 | |
| SCHEMBL13032088 | 0.80 | CA2 (0.35) | CA2FBP1 | |
| SCHEMBL13032075 | 0.78 | TRPV4 (0.39) | — | |
| SCHEMBL14931181 | 0.77 | TRPV4 (0.37) | — | |
| SCHEMBL3483772 | 0.77 | TRPV4 (0.36) | — | |
| SCHEMBL14931498 | 0.77 | TRPV4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | disclosed |