SCHEMBL1494417

SCHEMBL1494417

CCCCCCCCC[Si](C)(C)[O]

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
EPHX1 P07099 4/20 0.39
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
EPHX2 P34913 1/20 0.38
DNM1 Q05193 4/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17090824 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090807 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090815 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090809 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL1494494 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090822 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL2804365 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090765 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090838 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL1494268 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10854818-B2 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-12-01 US disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
US-10730904-B2 Method for liquid-phase synthesis of nucleic acid TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-08-04 US disclosed
EP-2921499-B1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACIDS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-22 EP disclosed
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
US-20190135852-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-05-09 US disclosed
US-20180138413-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-17 US disclosed
US-9966532-B2 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-08 US disclosed
US-9735374-B2 Metal complex and light-emitting device containing the metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-15 US disclosed
US-9705097-B2 Metal complex and light-emitting device containing the metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-20100019669-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-28 US disclosed
EP-2128168-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE Sumitomo Chemical Company, Limited (JP) 2009-12-02 EP disclosed
US-20090043064-A1 METAL COMPLEX, POLYMER COMPOUND, AND DEVICE CONTAINING IT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed
US-20090015139-A1 Organic electroluminescence device SUMITOMO CHEMICAL., CO., LTD. 2009-01-15 US disclosed
US-20080274303-A1 Polymer Compound and Polymer Light Emitting Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed
EP-1932851-A1 METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed
US-20070154732-A1 Dendrimer compound and organic luminescent device employing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-05 US disclosed
US-7157154-B2 Organoboron polymers; photoconductivity; inks; thin films; semiconductors; surface light sources; dot matrix displays SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-02 US disclosed
EP-1724294-A1 POLYMER AND POLYMERIC LUMINESCENT ELEMENT COMPRISING THE SAME Sumitomo Chemical Company, Limited (JP) 2006-11-22 EP disclosed
US-20050170202-A1 Polymer and polymeric luminescent element comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190135852-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID RNGTT, POLR2H, POLR2E TSHR 551/4885THRB 1506/4885EPHX1 2751/4885
US-10854818-B2 Dendrimer compound and organic luminescent device employing the same DCUN1D4, DCUN1D1, FLOT1 TSHR 3807/4885THRB 3244/4885EPHX1 3770/4885
US-20090043064-A1 METAL COMPLEX, POLYMER COMPOUND, AND DEVICE CONTAINING IT TIMCC, AP1M1, TXN TSHR 3303/4885THRB 4163/4885EPHX1 3617/4885
US-10730904-B2 Method for liquid-phase synthesis of nucleic acid RNGTT, POLR2H, POLR2E TSHR 411/4885THRB 1249/4885EPHX1 2124/4885
US-20180138413-A1 DENDRIMER COMPOUND AND ORGANIC LUMINESCENT DEVICE EMPLOYING THE SAME DCUN1D4, DCUN1D1, FLOT1 TSHR 3807/4885THRB 3244/4885EPHX1 3770/4885
US-20100019669-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE AP1M1, MRPL21, C1R TSHR 446/4885THRB 2848/4885EPHX1 3978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.