Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 15/20 | 0.36 |
| ▸ | CA1 | P00915 | 10/20 | 0.36 |
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15924708 | 0.82 | TAAR1 (0.53) | MGLLCA2CA1CA12CA4 | |
| SCHEMBL17540645 | 0.74 | TAAR1 (0.63) | TAAR1 | |
| SCHEMBL1873871 | 0.74 | CASP6 (0.37) | CA2CA1CA12CA7CA4 | |
| SCHEMBL31650638 | 0.73 | MEN1 (0.46) | — | |
| SCHEMBL8215818 | 0.73 | CA2 (0.39) | MGLLCA2CA1CA12CA7 | |
| SCHEMBL22791953 | 0.72 | LIPG (0.47) | — | |
| SCHEMBL22333721 | 0.72 | LIPG (0.47) | — | |
| SCHEMBL22748324 | 0.72 | LIPG (0.47) | — | |
| SCHEMBL27885744 | 0.72 | TAAR1 (0.39) | TAAR1 | |
| SCHEMBL1363756 | 0.72 | TAAR1 (0.46) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470528-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | Novartis AG (CH) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011023773-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2011-03-03 | — | — | WO | disclosed |