Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.30 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097718 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KMT2ATSHRMAPK1 | |
| SCHEMBL716796 | 0.82 | TSHR (0.47) | ALDH1A1MEN1KMT2ARECQLTSHR | |
| SCHEMBL2097313 | 0.80 | MAPT (0.38) | ALDH1A1MAPT | |
| SCHEMBL18116610 | 0.80 | SOD1 (0.42) | — | |
| SCHEMBL2094046 | 0.80 | MAPT (0.48) | MAPTTSHR | |
| SCHEMBL2089727 | 0.78 | CES2 (0.37) | — | |
| SCHEMBL3058241 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ARECQL | |
| SCHEMBL2097371 | 0.74 | SOD1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL13154651 | 0.74 | KMT2A (0.53) | ALDH1A1MAPTMEN1KMT2APLA2G2A | |
| SCHEMBL5378158 | 0.73 | ALDH1A1 (0.59) | ALDH1A1RECQLPLA2G2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192801-A1 | PEPTIDES DERIVATIVES | Bicycle Therapeutics Limited (GB) | 2017-07-19 | — | — | EP | disclosed |
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |