SCHEMBL2094046

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10359368	0.80	MAPT (0.55)	MAPTSOD1CYP2C19TSHRMRGPRX4
	SCHEMBL14944760	0.80	ALDH1A1 (0.33)	MAPTTSHR
	SCHEMBL2096242	0.77	WDR5 (0.59)	WDR5MAOBAOC3
	SCHEMBL9507394	0.75	MAPT (0.50)	MAPTSOD1CYP2C19TSHR
	SCHEMBL2272070	0.74	MAPT (0.59)	MAPTSOD1CYP2C19TSHRMRGPRX4
	SCHEMBL1547677	0.74	MAPT (0.54)	MAPTSOD1CYP2C19TSHRMRGPRX4
	SCHEMBL2090164	0.74	RAB9A (0.47)	MAPTCYP2C19MAOB
	SCHEMBL2094042	0.74	MAPT (0.48)	MAPTSOD1CYP2C19TSHRMRGPRX4
	SCHEMBL1547606	0.74	MAPT (0.48)	MAPTSOD1CYP2C19TSHRMRGPRX4
	SCHEMBL2089079	0.72	TSHR (0.42)	MAPTTSHRMRGPRX4TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.