Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18858529 | 0.89 | NOS3 (0.44) | NOS3NOS1NOS2SORT1ESR1 | |
| SCHEMBL10182085 | 0.78 | NOS3 (0.38) | NOS3NOS1NOS2SORT1ESR1 | |
| SCHEMBL18493106 | 0.77 | APLNR (0.36) | LNPEP | |
| SCHEMBL299637 | 0.76 | NOS2 (0.36) | NOS3NOS1NOS2CYP2D6HRH1 | |
| SCHEMBL97386 | 0.76 | CYP2D6 (0.35) | CYP2D6HRH1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30688732 | 0.76 | NOS2 (0.36) | NOS3NOS1NOS2CYP2D6HRH1 | |
| SCHEMBL21690800 | 0.75 | NOS3 (0.35) | NOS3NOS1NOS2ESR1ESR2 | |
| SCHEMBL22877018 | 0.74 | CYP2D6 (0.34) | CYP2D6HRH1HDAC1HDAC6CYP1A2 | |
| SCHEMBL2339199 | 0.74 | HRH1 (0.42) | HRH4CYP2D6HRH1CYP1A2CYP3A4 | |
| SCHEMBL309324 | 0.73 | NOS3 (0.44) | NOS3NOS1NOS2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220106319-A1 | JAK INHIBITOR AND PREPARATION METHOD THEREFOR | FELICAMED BIOTECHNOLOGY CO., LTD. (CN) | 2022-04-07 | — | — | US | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| US-20130123277-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123277-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR2C, HTR4 | NOS3 3084/4885NOS1 3809/4885NOS2 3708/4885 |
| US-20220106319-A1 | JAK INHIBITOR AND PREPARATION METHOD THEREFOR | JAK1, JAK2, JAK3 | NOS3 1152/4885NOS1 602/4885NOS2 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.