SCHEMBL14946149

SCHEMBL14946149

C#Cn1c2ccc(C)cc2c2cc(C(C)c3ccccc3)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
MLKL Q8NB16 1/20 0.33
PGR P06401 1/20 0.32
RORA P35398 1/20 0.32
RORC P51449 1/20 0.32
RORB Q92753 1/20 0.32
KMT2A Q03164 3/20 0.31
NR1I2 O75469 2/20 0.31
MEN1 O00255 2/20 0.31
AHR P35869 1/20 0.31
HTT P42858 1/20 0.31
LMNA P02545 1/20 0.30
EGFR P00533 1/20 0.30
ADRA2A P08913 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
TBXA2R P21731 1/20 0.30
PTGS2 P35354 1/20 0.30
OPRD1 P41143 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16303831 0.82 BCHE (0.50) BCHEACHEMLKLPGRRORA
SCHEMBL14946148 0.82 CYP1A2 (0.35) PGRRORARORCRORBADRA2A
SCHEMBL10114737 0.79 MAPT (0.43) PGRRORARORCRORBKMT2A
SCHEMBL16303832 0.78 BCHE (0.46) BCHEACHEPGRRORARORC
SCHEMBL10114707 0.72 MLKL (0.52) BCHEACHEMLKLKMT2AMEN1
SCHEMBL21374983 0.70 GPR3 (0.53) BCHEACHERORARORCRORB
SCHEMBL2846227 0.69 LMNA (0.50) ACHEKMT2AMEN1LMNA
SCHEMBL4668590 0.69 CYP2A6 (0.54) ADRA2A
SCHEMBL13772277 0.68 KDM4E (0.43) BCHEACHERORARORCRORB
SCHEMBL28054154 0.68 ACP3 (0.52) ACHELMNAOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130122710-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-16 US disclosed