Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730746 | 0.79 | KIF11 (0.43) | KIF11KCNH2SLC6A1SLC6A11PLA2G2A | |
| SCHEMBL12061903 | 0.78 | KIF11 (0.44) | KIF11HDAC3HDAC1HDAC2KCNH2 | |
| SCHEMBL7615687 | 0.77 | KIF11 (0.45) | KIF11KCNH2ALDH1A1SLC6A1SLC6A11 | |
| SCHEMBL3487683 | 0.77 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL16214813 | 0.77 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL15281845 | 0.76 | KIF11 (0.49) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL3490250 | 0.76 | KIF11 (0.49) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL9508740 | 0.76 | KIF11 (0.49) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL18349848 | 0.76 | TK1 (0.43) | KIF11KCNH2SLC6A1SLC6A11PLA2G2A | |
| SCHEMBL17359776 | 0.76 | PLA2G2A (0.39) | KIF11KCNH2SLC6A1SLC6A11PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637658-B2 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | KIF11 4673/4885HDAC3 1654/4885HDAC1 4147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.