Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915642 | 0.82 | GAA (0.41) | KIF11GAAALDH1A1KMT2ACNR2 | |
| SCHEMBL7616339 | 0.82 | MEN1 (0.44) | KIF11GAAALDH1A1KMT2ANPC1 | |
| SCHEMBL6516358 | 0.82 | HDAC1 (0.46) | GAAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL890354 | 0.80 | ALDH1A1 (0.46) | KIF11KCNH2ALDH1A1KMT2A | |
| SCHEMBL4915631 | 0.80 | POLB (0.38) | KIF11GAAALDH1A1KMT2ACNR2 | |
| SCHEMBL25631518 | 0.78 | KMT2A (0.45) | KMT2A | |
| SCHEMBL14946793 | 0.77 | KIF11 (0.41) | KIF11KCNH2ALDH1A1SLC6A1SLC6A11 | |
| SCHEMBL5964225 | 0.77 | GAA (0.43) | KIF11KCNH2GAAALDH1A1KMT2A | |
| SCHEMBL3839548 | 0.77 | GAA (0.43) | KIF11KCNH2GAAALDH1A1KMT2A | |
| Succinic Acid SCHEMBL6854675 | 0.77 | KIF11 (0.54) | KIF11KCNH2NPC1RAB9ASLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165569-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | Agilent Technologies, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056740-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | PROLINX, INC. (US) | 2000-09-28 | — | — | WO | disclosed |