Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287362 | 0.86 | PPARG (0.48) | PPARGPPARAALDH1A1HPGDCTBP2 | |
| SCHEMBL14950912 | 0.81 | ALDH1A1 (0.45) | PPARGPPARAMAOBALDH1A1LMNA | |
| SCHEMBL19230445 | 0.79 | CTNNB1 (0.51) | — | |
| SCHEMBL19230443 | 0.79 | CTNNB1 (0.51) | — | |
| SCHEMBL6688791 | 0.78 | PPARG (0.49) | PPARGPPARAMAOBALDH1A1HPGD | |
| SCHEMBL12341937 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9817764 | 0.77 | PPARG (0.44) | PPARGPPARAMAOBALDH1A1HPGD | |
| SCHEMBL8605469 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL890230 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL31112170 | 0.77 | PPARG (0.44) | PPARGPPARAMAOBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123169-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123169-A1 | PEPTIDOMIMETIC MACROCYCLES | GHRHR, GHSR, GHITM | PPARG 1000/4885PPARA 2437/4885MAOB 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.