SCHEMBL14948434

SCHEMBL14948434

Cc1ccc(N(c2ccc(C)cc2)c2cccc(CBr)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.46
CNR2 P34972 6/20 0.36
CNR1 P21554 3/20 0.36
TSHR P16473 3/20 0.35
ALDH1A1 P00352 3/20 0.35
TRPA1 O75762 1/20 0.35
MCHR1 Q99705 1/20 0.35
S1PR1 P21453 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
NPC1 O15118 1/20 0.34
JAK2 O60674 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
PAX8 Q06710 1/20 0.34
CETP P11597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13136832 0.85 CYP2C19 (0.44) CYP2C19
SCHEMBL21392008 0.85 CYP2C19 (0.44) CYP2C19
SCHEMBL14948466 0.85 TSHR (0.52) CYP2C19CNR2TSHRALDH1A1TRPA1
SCHEMBL18682086 0.84 RAB9A (0.44) CYP2C19CNR2TSHRALDH1A1TRPA1
SCHEMBL14948484 0.84 SIGMAR1 (0.38) CNR2TSHRALDH1A1TRPA1HTT
SCHEMBL24478732 0.82 CYP2C19 (0.42) CYP2C19CNR2CNR1TSHRALDH1A1
SCHEMBL21392007 0.82 CYP2C19 (0.42) CYP2C19CNR2CNR1TSHRALDH1A1
SCHEMBL12798297 0.82 CYP2C19 (0.50) CYP2C19CNR2CNR1TSHRALDH1A1
SCHEMBL12922778 0.82 ALDH1A1 (0.45) CYP2C19CNR2TSHRALDH1A1TRPA1
SCHEMBL22244129 0.81 BCL2 (0.41) CYP2C19ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed