SCHEMBL14948466

SCHEMBL14948466

BrCc1cccc(N(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
ALDH1A1 P00352 3/20 0.52
TRPA1 O75762 1/20 0.52
TDP1 Q9NUW8 2/20 0.40
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CNR2 P34972 1/20 0.40
OPRM1 P35372 2/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12922778 0.93 ALDH1A1 (0.45) TSHRALDH1A1TRPA1TDP1KDM4E
SCHEMBL14948484 0.86 SIGMAR1 (0.38) TSHRALDH1A1TRPA1KDM4EL3MBTL1
SCHEMBL14948434 0.85 CYP2C19 (0.46) TSHRALDH1A1TRPA1CYP2C19CNR2
SCHEMBL22698927 0.84 AGXT (0.41) TSHRALDH1A1TRPA1TDP1KDM4E
SCHEMBL14948464 0.84 TAAR1 (0.42) TSHRALDH1A1TRPA1TDP1SIGMAR1
SCHEMBL18682086 0.84 RAB9A (0.44) TSHRALDH1A1TRPA1CYP2C19CNR2
SCHEMBL18682169 0.82 TSHR (0.35) TSHRALDH1A1TRPA1TDP1KDM4E
SCHEMBL12957222 0.81 TP53 (0.54) TSHRTDP1CYP1A2CYP2D6MAPT
SCHEMBL7147284 0.80 ALDH1A1 (0.59) TSHRALDH1A1TRPA1TDP1KDM4E
SCHEMBL29582375 0.80 ALDH1A1 (0.59) TSHRALDH1A1TRPA1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed