SCHEMBL7147284

SCHEMBL7147284

BrCc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
TSHR P16473 3/20 0.59
TRPA1 O75762 1/20 0.59
TDP1 Q9NUW8 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP2C19 P33261 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CNR2 P34972 1/20 0.44
CRHBP P24387 1/20 0.42
ATM Q13315 1/20 0.42
CRHR2 Q13324 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29582375 1.00 ALDH1A1 (0.59) ALDH1A1TSHRTRPA1TDP1L3MBTL1
SCHEMBL29178568 0.90 ALDH1A1 (0.48) ALDH1A1TSHRTRPA1TDP1L3MBTL1
SCHEMBL16353258 0.88 ALDH1A1 (0.46) ALDH1A1TSHRTRPA1TDP1L3MBTL1
SCHEMBL12267968 0.85 ALDH1A1 (0.43) ALDH1A1TSHRTRPA1TDP1L3MBTL1
SCHEMBL27472062 0.82 TDP1 (0.62) ALDH1A1TSHRTRPA1TDP1L3MBTL1
SCHEMBL14948455 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTRPA1KDM4EMAPT
SCHEMBL14948466 0.80 TSHR (0.52) ALDH1A1TSHRTRPA1TDP1L3MBTL1
SCHEMBL24231223 0.80 ALDH1A1 (0.54) ALDH1A1TSHRTDP1L3MBTL1CYP2C19
SCHEMBL9561444 0.80 ALDH1A1 (0.54) ALDH1A1TSHRTDP1L3MBTL1CYP2C19
SCHEMBL9768685 0.80 CALM1 (0.55) ALDH1A1TSHRTDP1L3MBTL1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850002-B Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN disclosed
CN-115850002-B Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2025-05-23 CN disclosed
CN-115959962-A Visible light promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2023-04-14 CN disclosed
CN-115850002-A Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2023-03-28 CN disclosed
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed
US-20090043109-A1 ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE SENSOPATH TECHNOLOGIES, INC. 2009-02-12 US disclosed
CN-1119371-C Organosilicon-modified charge transporting compound and curable composition containing compound and having charge transporting ability DOW CORNING ASIA LTD (JP) 2003-08-27 CN disclosed
EP-0771805-B1 Silicon containing charge transport compounds and curable compositions thereof DOW CORNING ASIA LTD (JP) 2003-05-02 EP disclosed
US-5840816-A Method of manufacturing a polysiloxane charge transporting material DOW CORNING TORAY SILICONE CO., LTD. (JP) 1998-11-24 US disclosed
EP-0875791-A2 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1998-11-04 EP disclosed
US-5824443-A Method of manufacturing sililcon-type charge transporting materials DOW CORNING ASIA, LTD. (JP) 1998-10-20 US disclosed
CN-1156850-A Method for producing silicon-type charge transfer matter DOW CORNING ASIA LTD (JP) 1997-08-13 CN disclosed
CN-1156849-A Organosilicon-modified charge transporting compound and curable composition containing compound and having charge transporting ability DOW CORNING ASIA LTD (JP) 1997-08-13 CN disclosed
EP-0772091-A1 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1997-05-07 EP disclosed
EP-0771806-A1 Silicon containing charge transport compounds DOW CORNING ASIA, Ltd. (JP) 1997-05-07 EP disclosed
EP-0771805-A1 Silicon containing charge transport compounds and curable compositions thereof Dow Corning Asia, Ltd. (JP) 1997-05-07 EP disclosed
EP-0771809-A1 Method of manufacturing a polysiloxane charge transporting material DOW CORNING ASIA, Ltd. (JP) 1997-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043109-A1 ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE ALDH1B1, ALDH2, ALDH3A1 ALDH1A1 7/4885TSHR 3579/4885TRPA1 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.