Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CATSPER1 | Q8NEC5 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.68 |
| ▸ | MITF | O75030 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242849 | 0.91 | CATSPER1 (1.00) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL15891247 | 0.81 | ALDH1A1 (1.00) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL2117370 | 0.78 | ALDH1A1 (1.00) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL11605100 | 0.78 | NPC1 (0.71) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL8251473 | 0.75 | MAPT (0.62) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL8370261 | 0.73 | CATSPER1 (0.63) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL11602297 | 0.72 | CATSPER1 (0.64) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL11602301 | 0.72 | CATSPER1 (0.64) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL8372387 | 0.71 | ALDH1A1 (0.58) | CATSPER1MAPTALDH1A1MAPK1HTT | |
| SCHEMBL11604046 | 0.71 | CATSPER1 (0.63) | CATSPER1MAPTALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732050-B2 | Modulators of sperm hypermotility and uses thereof | HYDRA BIOSCIENCES, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150335622-A1 | MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2015-11-26 | — | — | US | disclosed |
| US-8952041-B2 | Modulators of sperm hypermobility and uses thereof | HYDRA BIOSCIENCES, INC. (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130123310-A1 | MODULATORS OF SPERM HYPERMOBILITY AND USES THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123310-A1 | MODULATORS OF SPERM HYPERMOBILITY AND USES THEREOF | CATSPER1, SPAG5, NASP | CATSPER1 1/4885MAPT 4340/4885ALDH1A1 630/4885 |
| US-20150335622-A1 | MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF | CATSPER1, SPAG5, ITPR3 | CATSPER1 1/4885MAPT 4125/4885ALDH1A1 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.