Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225673 | 0.84 | PTGS2 (0.44) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL27934992 | 0.82 | PTGS2 (0.43) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL892702 | 0.81 | MEN1 (0.49) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2468990 | 0.81 | PTGS2 (0.45) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL10971135 | 0.81 | PTGS2 (0.42) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL11420488 | 0.80 | NPSR1 (0.48) | ALDH1A1HPGDNPC1RAB9APTGS2 | |
| SCHEMBL22245510 | 0.77 | PTGS2 (0.52) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL8463065 | 0.77 | PTGS2 (0.56) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL12297897 | 0.77 | KMT2A (0.40) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL2929763 | 0.77 | PTGS1 (0.54) | ALDH1A1KMT2AMAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732050-B2 | Modulators of sperm hypermotility and uses thereof | HYDRA BIOSCIENCES, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150335622-A1 | MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2015-11-26 | — | — | US | disclosed |
| US-8952041-B2 | Modulators of sperm hypermobility and uses thereof | HYDRA BIOSCIENCES, INC. (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130123310-A1 | MODULATORS OF SPERM HYPERMOBILITY AND USES THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123310-A1 | MODULATORS OF SPERM HYPERMOBILITY AND USES THEREOF | CATSPER1, SPAG5, NASP | ALDH1A1 630/4885KMT2A 1636/4885MAPT 4340/4885 |
| US-20150335622-A1 | MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF | CATSPER1, SPAG5, ITPR3 | ALDH1A1 807/4885KMT2A 1670/4885MAPT 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.