Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938440 | 0.81 | RAB9A (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL14938438 | 0.81 | RAB9A (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL14938457 | 0.77 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1RAD51 | |
| SCHEMBL14938474 | 0.77 | SMN1; SMN2 (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL14938473 | 0.77 | SMN1; SMN2 (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL14938497 | 0.76 | LMNA (0.62) | SMN1; SMN2NPC1MAPTHTTMEN1 | |
| SCHEMBL14938495 | 0.76 | LMNA (0.62) | SMN1; SMN2NPC1MAPTHTTMEN1 | |
| SCHEMBL14938483 | 0.76 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL1416168 | 0.76 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| Phenyl Methylcarbamate SCHEMBL27868174 | 0.75 | CYP1A2 (0.55) | RAB9ASMN1; SMN2ALDH1A1MAPTRAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |