Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093208 | 0.81 | ALDH1A1 (0.48) | HTR2CHTR2BMAPTTDP1L3MBTL1 | |
| SCHEMBL27520016 | 0.77 | NR3C1 (0.36) | HTR2CHTR2BMAOBMAOAMAPK1 | |
| SCHEMBL7032381 | 0.74 | KDM4E (0.50) | MAOBMAPTTDP1KDM4EALDH1A1 | |
| SCHEMBL8093303 | 0.74 | ANPEP (0.41) | HTR2CHTR2BMAOBMAOAMAPT | |
| SCHEMBL27279995 | 0.74 | KDM4E (0.45) | HTR2CHTR2BMAOBMAOAMAPT | |
| SCHEMBL128290 | 0.74 | AR (0.49) | MAOBMAOAMAPTTDP1L3MBTL1 | |
| SCHEMBL19746 | 0.73 | CYP19A1 (0.45) | SLC6A3MAOBMAOAMAPTKDM4E | |
| SCHEMBL13704045 | 0.72 | HTR1A (0.58) | TNKS2HTR2CHTR2BHTR1ASLC6A2 | |
| SCHEMBL11040351 | 0.72 | CA2 (0.50) | TNKS2HTR2CHTR2BHTR1ASLC6A2 | |
| SCHEMBL4444342 | 0.72 | ROR1 (0.43) | MAOBMAOAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765420-B2 | Method for preparing pterocarpan | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-07-01 | — | — | US | disclosed |
| US-20130130332-A1 | NOVEL METHOD FOR PREPARING PTEROCARPAN | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-05-23 | — | — | US | disclosed |