Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 5/20 | 0.33 |
| ▸ | MMP3 | P08254 | 5/20 | 0.33 |
| ▸ | MMP9 | P14780 | 5/20 | 0.33 |
| ▸ | MMP8 | P22894 | 5/20 | 0.33 |
| ▸ | MMP13 | P45452 | 5/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542294 | 0.67 | MMP9 (0.56) | KMT2AMEN1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL4951081 | 0.67 | GAA (0.37) | MAPTGAAMMP2MMP3MMP9 | |
| SCHEMBL8698469 | 0.67 | ALDH1A1 (0.46) | KMT2AALDH1A1MMP2 | |
| SCHEMBL328467 | 0.65 | MMP1 (0.50) | ALDH1A1MMP2MMP3MMP9MMP8 | |
| P-Xylene SCHEMBL11354414 | 0.62 | TSHR (0.50) | ALDH1A1RAB9AGAATSHR | |
| SCHEMBL3784376 | 0.62 | ALDH1A1 (0.41) | KMT2AALDH1A1MMP2 | |
| SCHEMBL3783631 | 0.62 | ALDH1A1 (0.41) | KMT2AALDH1A1MMP2 | |
| SCHEMBL17560328 | 0.61 | PDK1 (0.41) | MAPTTSHR | |
| SCHEMBL12942975 | 0.60 | SLC18A2 (0.34) | MAPTGAAMMP2MMP3MMP9 | |
| SCHEMBL15934092 | 0.59 | KDM4E (0.47) | ALDH1A1MAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511488-B1 | HUMAN ADAM-10 INHIBITORS | SYMPHONY EVOLUTION INC (US) | 2013-05-22 | — | — | EP | disclosed |