Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.63 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 3/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960226 | 1.00 | GABRA1 (0.63) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL14960248 | 0.87 | GABRA1 (0.67) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL31696017 | 0.87 | OPRK1 (0.69) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL26767935 | 0.86 | GABRA1 (0.50) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL13524252 | 0.85 | GABRA1 (0.65) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL13523787 | 0.84 | GABRA3 (0.49) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL2922460 | 0.81 | GABRA1 (0.55) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL2923658 | 0.81 | GABRA1 (0.55) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL2615366 | 0.81 | OPRK1 (0.55) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL2928698 | 0.81 | LMNA (0.55) | GABRA1GABRA5GABRA2GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231623-B1 | 5-PHENYL-1H-BENZO[E][1, 4]DIAZEPINE COMPOUNDS SUBSTITUTED WITH AN HYDROXAMIC ACID GROUP AS HISTONE DEACETYLASE INHIBITORS | UNIV FIRENZE (IT) | 2013-05-22 | — | — | EP | disclosed |