SCHEMBL25399783

SCHEMBL25399783

ON=Cc1cccc(-c2ccccc2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
NPC1 O15118 1/20 0.49
ASIC3 Q9UHC3 1/20 0.46
KDM4E B2RXH2 2/20 0.45
HSP90AA1 P07900 2/20 0.42
P2RX7 Q99572 1/20 0.40
HPGD P15428 2/20 0.40
GFER P55789 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 3/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FGF23 Q9GZV9 1/20 0.39
GUSB P08236 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
AURKA O14965 1/20 0.35
PRKACA P17612 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14960439 0.86 RAB9A (0.52) RAB9ANPC1KDM4EHSP90AA1P2RX7
SCHEMBL11602459 0.80 RAB9A (0.57) RAB9ANPC1KDM4EHSP90AA1P2RX7
SCHEMBL21397879 0.80 RAB9A (0.57) RAB9ANPC1KDM4EHSP90AA1P2RX7
SCHEMBL20399817 0.79 HSP90AA1 (0.61) RAB9AMEN1KMT2ANPC1KDM4E
SCHEMBL20399818 0.79 HSP90AA1 (0.61) RAB9AMEN1KMT2ANPC1KDM4E
SCHEMBL20412773 0.79 HSP90AA1 (0.61) RAB9AMEN1KMT2ANPC1KDM4E
SCHEMBL2306654 0.78 CTSS (0.52) RAB9AMEN1KMT2ANPC1KDM4E
SCHEMBL2306650 0.78 CTSS (0.52) RAB9AMEN1KMT2ANPC1KDM4E
SCHEMBL13304089 0.77 GUSB (0.45) RAB9AMEN1KMT2ANPC1ASIC3
SCHEMBL12728662 0.75 MEN1 (0.46) RAB9AMEN1KMT2ANPC1ASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-116568310-A Boric acid compounds 株式会社LG化学 2023-08-08 CN disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 RAB9A 715/4885MEN1 800/4885KMT2A 2072/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 RAB9A 931/4885MEN1 386/4885KMT2A 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.