Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL308073 | 0.90 | HSD17B10 (0.54) | HSD17B10KDM4ESLC6A9GLRA1OR51E2 | |
| Tetraxetan SCHEMBL3364489 | 0.90 | HSD17B10 (0.54) | HSD17B10KDM4ESLC6A9GLRA1OR51E2 | |
| SCHEMBL8036117 | 0.88 | KDM4E (0.58) | HSD17B10KDM4ESLC6A9POLBPKM | |
| SCHEMBL16731723 | 0.88 | KDM4E (0.58) | HSD17B10KDM4ESLC6A9POLBPKM | |
| SCHEMBL15043622 | 0.88 | KDM4E (0.58) | HSD17B10KDM4ESLC6A9POLBPKM | |
| SCHEMBL26105210 | 0.88 | KDM4E (0.58) | HSD17B10KDM4ESLC6A9POLBPKM | |
| Tetraxetan SCHEMBL21248095 | 0.87 | HSD17B10 (0.56) | HSD17B10KDM4ESLC6A9POLBPKM | |
| SCHEMBL10562348 | 0.86 | KDM4E (0.56) | HSD17B10KDM4ESLC6A9POLBPKM | |
| SCHEMBL6848102 | 0.84 | HSD17B10 (0.64) | HSD17B10KDM4ESLC6A9TSHRS1PR1 | |
| SCHEMBL173508 | 0.84 | HSD17B10 (0.64) | HSD17B10KDM4ESLC6A9TSHRS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331012-A1 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.p.A. (IT) | 2003-07-30 | — | — | EP | claimed |
| US-8318134-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2012-11-27 | — | — | US | disclosed |
| EP-1469890-B1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2011-08-10 | — | — | EP | disclosed |
| EP-2298362-A1 | Responsive paramagnetic MRI contrast agents | Bracco Imaging S.p.A (IT) | 2011-03-23 | — | — | EP | disclosed |
| US-20090234221-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2009-09-17 | — | — | US | disclosed |
| US-7524483-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2009-04-28 | — | — | US | disclosed |
| US-20050191243-A1 | Responsive paramagnetic mri contrast agents | BRACCO IMAGING S.P.A. (IT) | 2005-09-01 | — | — | US | disclosed |
| EP-1469890-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | Bracco Imaging S.p.A. (IT) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063912-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2003-08-07 | — | — | WO | disclosed |
| EP-1331012-A1 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.p.A. (IT) | 2003-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234221-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | MYT1, PRTN3, CECR2 | HSD17B10 4757/4885KDM4E 3172/4885SLC6A9 343/4885 |
| US-20050191243-A1 | Responsive paramagnetic mri contrast agents | MYT1, PRTN3, CECR2 | HSD17B10 4757/4885KDM4E 3172/4885SLC6A9 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.