Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984072 | 0.89 | IDO1 (0.36) | IDO1 | |
| SCHEMBL14964343 | 0.87 | IDO1 (0.35) | IDO1 | |
| SCHEMBL14964339 | 0.87 | MAPK1 (0.32) | IDO1TDO2ALDH1A1 | |
| SCHEMBL14964338 | 0.85 | IDO1 (0.35) | IDO1TDO2ALDH1A1 | |
| SCHEMBL14964245 | 0.85 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL14964193 | 0.85 | ALDH1A1 (0.31) | IDO1TDO2ALDH1A1 | |
| SCHEMBL14964328 | 0.84 | IDO1 (0.37) | IDO1TDO2ALDH1A1 | |
| SCHEMBL14964261 | 0.83 | CYP2A13 (0.37) | IDO1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL16581715 | 0.83 | TBXAS1 (0.34) | IDO1 | |
| SCHEMBL14964185 | 0.82 | POLB (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |