Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964226 | 0.84 | STAT5B (0.41) | L3MBTL1ALDH1A1HPGD | |
| SCHEMBL14964309 | 0.84 | L3MBTL1 (0.31) | L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL14462671 | 0.83 | KMT2A (0.45) | KMT2AL3MBTL1POLBTP53ALDH1A1 | |
| SCHEMBL14964365 | 0.82 | HDAC6 (0.38) | SMN1; SMN2 | |
| SCHEMBL14964281 | 0.81 | — | — | |
| SCHEMBL14964193 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL14964196 | 0.79 | IDO1 (0.32) | ALDH1A1 | |
| SCHEMBL5630859 | 0.79 | KMT2A (0.44) | KMT2AL3MBTL1POLBTP53ALDH1A1 | |
| SCHEMBL5630868 | 0.79 | KMT2A (0.44) | KMT2AL3MBTL1POLBTP53ALDH1A1 | |
| SCHEMBL14964277 | 0.78 | IDO1 (0.32) | L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |