Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964200 | 0.84 | KMT2A (0.44) | L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL14462761 | 0.83 | MAPT (0.38) | L3MBTL1SMN1; SMN2IDO1POLBMAPT | |
| SCHEMBL14964365 | 0.82 | HDAC6 (0.38) | SMN1; SMN2IDO1 | |
| SCHEMBL14964193 | 0.81 | ALDH1A1 (0.31) | IDO1 | |
| SCHEMBL14964185 | 0.80 | POLB (0.32) | SMN1; SMN2POLB | |
| SCHEMBL14964281 | 0.79 | — | — | |
| SCHEMBL14964196 | 0.79 | IDO1 (0.32) | IDO1 | |
| SCHEMBL5631439 | 0.79 | MAPT (0.37) | L3MBTL1SMN1; SMN2IDO1POLBMAPT | |
| SCHEMBL5631445 | 0.79 | MAPT (0.37) | L3MBTL1SMN1; SMN2IDO1POLBMAPT | |
| SCHEMBL14964277 | 0.78 | IDO1 (0.32) | L3MBTL1SMN1; SMN2IDO1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |