Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.53 |
| ▸ | BCHE | P06276 | 11/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28172778 | 1.00 | ACHE (0.53) | ACHEBCHEFAAHMARK4CHRNB2 | |
| SCHEMBL3629562 | 0.79 | ACHE (0.51) | ACHEBCHEFAAHMARK4CHRNB2 | |
| SCHEMBL27737822 | 0.77 | HTR3E (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL2089293 | 0.77 | LMNA (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL2092433 | 0.77 | SCN2A (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL20278104 | 0.75 | MTNR1A (0.57) | — | |
| SCHEMBL30445047 | 0.75 | LMNA (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| Benzene SCHEMBL1720409 | 0.75 | CHRNB2 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL442790 | 0.75 | CHRNB2 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL5070892 | 0.74 | ACHE (0.46) | ACHEBCHEFAAHMARK4CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780006-A1 | COMPOSITION FOR TRANSDERMAL ADMINISTRATION OF RIVASTIGMINE | tesa Labtec GmbH (DE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072062-A1 | COMPOSITION FOR TRANSDERMAL ADMINISTRATION OF RIVASTIGMINE | LABTEC GMBH (DE) | 2013-05-23 | — | — | WO | disclosed |