SCHEMBL14965495

SCHEMBL14965495

O=P(O)(O)C(I)c1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
MMP2 P08253 1/20 0.45
PGK1 P00558 2/20 0.43
PGK2 P07205 2/20 0.43
ESR1 P03372 7/20 0.41
ESR2 Q92731 6/20 0.41
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
LMNA P02545 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.37
ALOX15 P16050 2/20 0.37
CYP1A2 P05177 1/20 0.37
PGR P06401 1/20 0.37
CHRM2 P08172 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
AR P10275 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18486636 0.79 SRC (0.60) CA12PGK1PGK2SRCCA9
SCHEMBL10454829 0.76 ACP3 (0.59) CA12CA1CA2MMP2PGK1
SCHEMBL5936840 0.76 SRC (0.62) CA12CA1CA2MMP2PGK1
Hydrochloric Acid SCHEMBL5935336 0.76 CA12 (0.44) CA12CA1CA2MMP2PGK1
SCHEMBL10252598 0.74 PGK1 (0.61) CA12CA1CA2MMP2PGK1
SCHEMBL2199107 0.73 ESR1 (0.52) CA12CA1CA2MMP2PGK1
Hydroquinone SCHEMBL329315 0.71 CA12 (0.61) CA12CA1CA2MMP2ESR1
Hydroquinone SCHEMBL131228 0.71 CA12 (0.61) CA12CA1CA2MMP2ESR1
SCHEMBL22863240 0.70 SRC (0.50) CA12CA1CA2ESR1ESR2
SCHEMBL18825592 0.70 PGK1 (0.45) CA12CA1CA2MMP2PGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405519-A1 ADDITIVE MIXTURE FOR STABILIZATION OF POLYOL AND POLYURETHANE BASF SE (DE) 2018-11-28 EP disclosed
EP-3334780-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2018-06-20 EP disclosed
WO-2017125291-A1 ADDITIVE MIXTURE FOR STABILIZATION OF POLYOL AND POLYURETHANE BASF SE (DE) 2017-07-27 WO disclosed
WO-2017025431-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2017-02-16 WO disclosed
EP-2780409-A1 ORGANIC SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2014-09-24 EP disclosed
WO-2013072853-A1 ORGANIC SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2013-05-23 WO disclosed
CN-101189248-A Novel phosphorus-containing thyromimetics METABASIS THERAPEUTICS INC (US) 2008-05-28 CN disclosed
CN-1882327-A Novel phosphorus-containing thyromimetics METABASIS THERAPEUTICS INC (US) 2006-12-20 CN disclosed