Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.45 |
| ▸ | PGK2 | P07205 | 3/20 | 0.45 |
| ▸ | ACP3 | P15309 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454292 | 0.81 | ACP3 (0.66) | PGK1PGK2ACP3 | |
| SCHEMBL15156753 | 0.79 | ESR1 (0.43) | ACP3CA12CA1CA2MMP2 | |
| SCHEMBL11027911 | 0.78 | GRM8 (0.44) | PGK1PGK2CA12CA1CA2 | |
| SCHEMBL5058077 | 0.77 | ACP3 (0.40) | PGK1PGK2ACP3CYP1A2LMNA | |
| SCHEMBL3234995 | 0.76 | FDPS (0.46) | ACP3CYP1A2LMNAMAPTESR1 | |
| SCHEMBL18825582 | 0.73 | LMNA (0.51) | ACP3CYP1A2LMNASMN1; SMN2PTGS1 | |
| SCHEMBL5936840 | 0.73 | SRC (0.62) | PGK1PGK2ACP3CA12CA1 | |
| SCHEMBL10454829 | 0.73 | ACP3 (0.59) | PGK1PGK2ACP3CA12CA1 | |
| SCHEMBL10252598 | 0.71 | PGK1 (0.61) | PGK1PGK2CA12CA1CA2 | |
| SCHEMBL11402377 | 0.70 | ACP3 (0.47) | PGK1PGK2ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533612-A | Bone-targeting antimicrobial oxazolidinone-related compounds, formulations thereof, and uses thereof | 弗兰克·哈洛克·埃比蒂诺 | 2021-03-19 | — | — | CN | claimed |
| WO-2017079260-A1 | PHOSPHONATE-CHLOROQUINE CONJUGATES AND METHODS USING SAME | UNIVERSITY OF ROCHESTER (US) | 2017-05-11 | — | — | WO | disclosed |