Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966114 | 0.84 | KCNH2 (0.38) | KCNH2POLBCHRM1HIF1ALMNA | |
| SCHEMBL14965833 | 0.79 | KCNH2 (0.41) | KCNH2POLBPTGS1SLC6A2SLC6A4 | |
| SCHEMBL14966242 | 0.76 | LMNA (0.44) | POLBKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14965776 | 0.76 | KCNH2 (0.42) | KCNH2PTGS1SLC6A2SLC6A4CHRM1 | |
| SCHEMBL14965644 | 0.75 | CA1 (0.46) | KCNH2POLBKMT2AHIF1ALMNA | |
| SCHEMBL14966217 | 0.74 | CHRM1 (0.50) | KCNH2PTGS1SLC6A2SLC6A4CHRM1 | |
| SCHEMBL5542906 | 0.73 | KCNH2 (0.50) | KCNH2POLBPTGS1SLC6A2SLC6A4 | |
| SCHEMBL14966362 | 0.71 | KCNH2 (0.39) | KCNH2POLBPTGS1SLC6A2SLC6A4 | |
| SCHEMBL14966219 | 0.71 | CA1 (0.48) | KCNH2POLBCHRM1KMT2ANPC1 | |
| SCHEMBL5535426 | 0.70 | KCNH2 (0.52) | KCNH2PTGS1SLC6A2SLC6A4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |