Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 18/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | AADAC | P22760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965709 | 0.89 | CHRM1 (0.46) | EPHX2CHRM1FAAH | |
| SCHEMBL14965973 | 0.88 | CHRM1 (0.51) | EPHX2CHRM1FAAH | |
| SCHEMBL14965755 | 0.88 | EPHX2 (0.50) | EPHX2CHRM1 | |
| SCHEMBL14965836 | 0.83 | MCHR1 (0.41) | EPHX2CHRM1 | |
| SCHEMBL29433970 | 0.82 | CHRM1 (0.61) | EPHX2EPHX1CHRM1 | |
| SCHEMBL14965608 | 0.82 | CHRM1 (0.48) | EPHX2CHRM1 | |
| SCHEMBL14966094 | 0.80 | PDE7A (0.33) | CHRM1 | |
| SCHEMBL14971162 | 0.78 | DRD2 (0.38) | CHRM1 | |
| SCHEMBL14965586 | 0.76 | EPHX2 (0.51) | EPHX2CHRM1 | |
| SCHEMBL14965637 | 0.75 | CHRM1 (0.51) | EPHX2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |