Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 4/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965802 | 0.89 | L3MBTL3 (0.43) | HSD11B1MGLLL3MBTL3L3MBTL1SCN9A | |
| SCHEMBL14965755 | 0.88 | EPHX2 (0.50) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL14965709 | 0.86 | CHRM1 (0.46) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL14965843 | 0.86 | CHRM1 (0.48) | CHRM1KCNH2HSD11B1MGLLMAPK7 | |
| SCHEMBL14965688 | 0.83 | RBP4 (0.45) | HSD11B1MGLLL3MBTL3L3MBTL1SCN9A | |
| SCHEMBL14965524 | 0.82 | CHRM1 (0.51) | CHRM1KCNH2HSD11B1MGLLMAPK7 | |
| SCHEMBL14965973 | 0.82 | CHRM1 (0.51) | CHRM1KCNH2L3MBTL1PTGS1SLC6A2 | |
| SCHEMBL14965728 | 0.82 | EPHX2 (0.47) | CHRM1EPHX2 | |
| SCHEMBL5546331 | 0.81 | KCNH2 (0.59) | CHRM1KCNH2HSD11B1MGLLMAPK7 | |
| SCHEMBL5546337 | 0.81 | KCNH2 (0.59) | CHRM1KCNH2HSD11B1MGLLMAPK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |