SCHEMBL14966710

SCHEMBL14966710

CCOC(=O)C1OC1(CC)CC

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.39
ALDH1A1 P00352 3/20 0.37
LMNA P02545 3/20 0.37
PPM1B O75688 1/20 0.37
PTPN1 P18031 1/20 0.37
PPP1CC P36873 1/20 0.37
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX15 P16050 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967904 0.84 PPM1B (0.40) ALDH1A1LMNAPPM1BPTPN1PPP1CC
SCHEMBL900783 0.78 LMNA (0.43) SOAT1ALDH1A1LMNAPPM1BPTPN1
SCHEMBL14967972 0.78 NAAA (0.46) ALDH1A1LMNATSHR
SCHEMBL2139493 0.78 LMNA (0.40) ALDH1A1LMNAPPM1BPTPN1PPP1CC
SCHEMBL17309112 0.71 TSHR (0.43) SOAT1ALDH1A1LMNAPPM1BPTPN1
SCHEMBL14968041 0.71 ALDH1A1 (0.53) ALDH1A1LMNAPPM1BPTPN1PPP1CC
SCHEMBL2027200 0.71 ALDH1A1 (0.49) ALDH1A1LMNAPPM1BPTPN1PPP1CC
SCHEMBL14967544 0.70 ALDH1A1 (0.41) ALDH1A1POLBTSHRGAAKDM4E
SCHEMBL9120224 0.69 LMNA (0.33) SOAT1ALDH1A1LMNAPPM1BPTPN1
SCHEMBL14967474 0.69 ALDH1A1 (0.55) ALDH1A1LMNAPPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed