SCHEMBL2139493

SCHEMBL2139493

CCOC(=O)C1OC1(C)CC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
PPM1B O75688 1/20 0.40
PTPN1 P18031 1/20 0.40
PPP1CC P36873 1/20 0.40
POLB P06746 1/20 0.38
ALDH1A1 P00352 4/20 0.37
MAPT P10636 3/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967693 0.85 PPM1B (0.42) LMNAPPM1BPTPN1PPP1CCALDH1A1
SCHEMBL14967933 0.82 ALDH1A1 (0.42) LMNAPPM1BPTPN1PPP1CCPOLB
SCHEMBL9692238 0.82 ALDH1A1 (0.37) LMNAPPM1BPTPN1PPP1CCPOLB
SCHEMBL9691853 0.82 PPM1B (0.32) PPM1BPTPN1PPP1CCALDH1A1MAPT
SCHEMBL900783 0.81 LMNA (0.43) LMNAPPM1BPTPN1PPP1CCPOLB
SCHEMBL14968059 0.81 EPHX1 (0.33) PPM1BPTPN1PPP1CC
SCHEMBL14966710 0.78 SOAT1 (0.39) LMNAPPM1BPTPN1PPP1CCPOLB
SCHEMBL14967984 0.77 ALDH1A1 (0.33) LMNAPOLBALDH1A1MAPTTSHR
SCHEMBL14967324 0.77 MAPK1 (0.36)
SCHEMBL14967987 0.74 EPHX1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101248092-B Functionalized polymers and tires improved therefrom BRIDGESTONE CORP 2012-12-05 CN claimed
EP-1924608-B1 FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM BRIDGESTONE CORP (JP) 2010-01-27 EP claimed
CN-101248092-A Functionalized polymers and tires improved therefrom BRIDGESTONE CORP (JP) 2008-08-20 CN claimed
EP-1924608-A2 FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM Bridgestone Corporation (JP) 2008-05-28 EP claimed
US-20070054995-A1 Functionalized polymers and improved tires therefrom BRIDGESTONE CORPORATION (JP) 2007-03-08 US claimed
WO-2007024797-A2 FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM BRIDGESTONE CORPORATION (JP) 2007-03-01 WO claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed
EP-2111443-A2 BENEFIT AGENT DELIVERY COMPOSITIONS The Procter and Gamble Company (US) 2009-10-28 EP disclosed
US-20080200363-A1 Perfumes, brighteners, insect repellants, flavors, vitamins, fabric softeners, skin care agents; increasing potency, reducing cost PROECTER & GAMBLE COMPANY, THE 2008-08-21 US disclosed
WO-2008100601-A2 BENEFIT AGENT DELIVERY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2008-08-21 WO disclosed
CN-101248092-A Functionalized polymers and tires improved therefrom BRIDGESTONE CORP (JP) 2008-08-20 CN disclosed
EP-1924608-A2 FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM Bridgestone Corporation (JP) 2008-05-28 EP disclosed
US-20070054995-A1 Functionalized polymers and improved tires therefrom BRIDGESTONE CORPORATION (JP) 2007-03-08 US disclosed
WO-2007024797-A2 FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM BRIDGESTONE CORPORATION (JP) 2007-03-01 WO disclosed