SCHEMBL14966918

SCHEMBL14966918

COc1ccc(C2(C(=O)Oc3ccccc3)OC2(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
GAA P10253 2/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
FAAH O00519 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 2/20 0.42
KMT2A Q03164 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 1/20 0.40
CA4 P22748 1/20 0.40
LTA4H P09960 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109920 0.99 GAA (0.42) ALDH1A1GAAHTTSMN1; SMN2FAAH
SCHEMBL14967731 0.88 L3MBTL1 (0.42) ALDH1A1FAAHMAPTKMT2AL3MBTL1
SCHEMBL14967992 0.87 RAB9A (0.43) ALDH1A1GAAHTTSMN1; SMN2FAAH
SCHEMBL14967348 0.87 POLB (0.41) ALDH1A1GAANPC1RAB9AMAPT
SCHEMBL16110175 0.83 CA1 (0.42) HTTSMN1; SMN2NPC1RAB9AMAPT
SCHEMBL14967512 0.82 CA1 (0.44) SMN1; SMN2NPC1RAB9AMAPTMAPK1
SCHEMBL14967817 0.81 FAAH (0.50) ALDH1A1GAAHTTSMN1; SMN2FAAH
SCHEMBL14968020 0.81 FAAH (0.47) ALDH1A1GAAHTTSMN1; SMN2FAAH
SCHEMBL14969500 0.80 FAAH (0.52) ALDH1A1GAAHTTSMN1; SMN2FAAH
SCHEMBL14967624 0.80 CHRM1 (0.42) ALDH1A1NPC1RAB9AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed