SCHEMBL14967286

SCHEMBL14967286

CC(C)(C)OC(=O)C1(c2ccccc2)OC1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RORC P51449 10/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
ABCB1 P08183 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
KDM1A O60341 1/20 0.37
MAOB P27338 1/20 0.37
RECQL P46063 1/20 0.34
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109703 0.92 RORC (0.38) RORCL3MBTL1ABCB1CYP3A4ALOX15
SCHEMBL14967746 0.90 EDNRA (0.40) RORCL3MBTL1MAOBRECQLKMT2A
SCHEMBL14967147 0.84 ADORA2B (0.33) RORCMAOBKMT2A
SCHEMBL14968177 0.83 CYP3A4 (0.51) CYP3A4ALOX15HTTKMT2ANPSR1
SCHEMBL14967648 0.82 BACE1 (0.36) L3MBTL1RECQLKMT2ATSHR
SCHEMBL14967798 0.79 TSHR (0.47) L3MBTL1HTTKMT2ATSHR
SCHEMBL14968092 0.79 CYP3A4 (0.38) RORCL3MBTL1CYP3A4ALOX15HTT
SCHEMBL14967416 0.79 L3MBTL1 (0.42) RORCL3MBTL1ABCB1KDM1AMAOB
SCHEMBL14968090 0.79 ALDH1A1 (0.40) L3MBTL1ABCB1CYP3A4ALOX15HTT
SCHEMBL16110308 0.78 MAOB (0.39) MAOBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed