SCHEMBL14967147

SCHEMBL14967147

Cc1ccc(C2OC2(C(=O)OC(C)(C)C)c2ccc(C)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 2/20 0.33
GPR119 Q8TDV5 1/20 0.33
RORC P51449 4/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
MAOB P27338 1/20 0.30
RAB9A P51151 1/20 0.30
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109703 0.93 RORC (0.38) RORCLMNAMAOB
SCHEMBL16110308 0.92 MAOB (0.39) ALDH1A1LMNANPC1MAPTMAOB
SCHEMBL14967648 0.86 BACE1 (0.36) KMT2AALDH1A1LMNANPC1MAPT
SCHEMBL14967286 0.84 RORC (0.39) RORCKMT2AMAOB
SCHEMBL16109648 0.84 TDP1 (0.37) KMT2AALDH1A1LMNAMAPTMAOB
SCHEMBL14967851 0.81 OPRM1 (0.44) KMT2AALDH1A1MAPT
SCHEMBL14967746 0.80 EDNRA (0.40) RORCKMT2AALDH1A1NPC1MAPT
SCHEMBL14967090 0.80 ABHD10 (0.37) ADORA2BKMT2AALDH1A1LMNANPC1
SCHEMBL16108695 0.79 GPR119 (0.35) ADORA2BGPR119KMT2AALDH1A1LMNA
SCHEMBL14968239 0.79 SCN1A (0.37) ADORA2BKMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed