SCHEMBL14967368

SCHEMBL14967368

CCOC(=O)C1(c2ccc(OC)cc2)OC1c1ccc(OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.48
GAA P10253 4/20 0.48
LMNA P02545 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HTT P42858 1/20 0.44
KMT2A Q03164 3/20 0.44
TSHR P16473 2/20 0.44
MEN1 O00255 1/20 0.44
NPSR1 Q6W5P4 3/20 0.40
CACNA1D Q01668 1/20 0.40
USP2 O75604 1/20 0.38
GLA P06280 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16108991 0.96 ALDH1A1 (0.45) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL14967931 0.94 ALDH1A1 (0.46) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL14967013 0.90 MIF (0.41) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL14967936 0.90 ALDH1A1 (0.40) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL16109754 0.88 ALDH1A1 (0.40) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL16109608 0.88 ALDH1A1 (0.40) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL14967851 0.87 OPRM1 (0.44) ALDH1A1GAAKDM4EHTTKMT2A
SCHEMBL14967096 0.87 MIF (0.39) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL14967655 0.86 HSD17B10 (0.39) ALDH1A1GAALMNAKDM4EHPGD
SCHEMBL14968057 0.86 OPRK1 (0.41) ALDH1A1GAALMNAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed