SCHEMBL14967425

SCHEMBL14967425

CCC1(C)OC1C(=O)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.39
USP2 O75604 1/20 0.39
TP53 P04637 1/20 0.39
ELANE P08246 3/20 0.39
GAA P10253 2/20 0.38
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
ABCB1 P08183 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967544 0.83 ALDH1A1 (0.41) POLBCHRM2CHRM4CHRM5CHRM1
SCHEMBL14968285 0.82 ALDH1A1 (0.45) POLBL3MBTL1ALDH1A1ELANEGAA
SCHEMBL14967432 0.79 ELANE (0.38) POLBCHRM2CHRM4CHRM5CHRM1
SCHEMBL16109691 0.78 ALDH1A1 (0.41) POLBL3MBTL1ALDH1A1ELANEGAA
SCHEMBL16108688 0.75 USP2 (0.36) ALDH1A1TSHRUSP2TP53ELANE
SCHEMBL16110269 0.74 ALDH1A1 (0.40) L3MBTL1ALDH1A1ELANEGAAMAPT
SCHEMBL14967009 0.73 FAAH (0.43) POLBALDH1A1ELANERAB9A
SCHEMBL14967125 0.73 ALDH1A1 (0.41) POLBL3MBTL1ALDH1A1ELANEGAA
SCHEMBL16109556 0.73 USP2 (0.40) POLBL3MBTL1ALDH1A1USP2MAPT
SCHEMBL14968010 0.72 ALDH1A1 (0.42) POLBL3MBTL1ALDH1A1ELANEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed