SCHEMBL14968285

SCHEMBL14968285

CC1(C)OC1C(=O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 3/20 0.41
POLB P06746 2/20 0.41
ELANE P08246 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.39
ATM Q13315 2/20 0.39
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
FABP7 O15540 1/20 0.37
FABP3 P05413 1/20 0.37
FABP5 Q01469 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109691 0.84 ALDH1A1 (0.41) ALDH1A1L3MBTL1POLBELANETDP1
SCHEMBL14967425 0.82 POLB (0.40) ALDH1A1L3MBTL1POLBELANEMAPT
SCHEMBL14967544 0.80 ALDH1A1 (0.41) ALDH1A1L3MBTL1POLBELANETDP1
SCHEMBL16109556 0.79 USP2 (0.40) ALDH1A1L3MBTL1POLBMAPT
SCHEMBL14968010 0.79 ALDH1A1 (0.42) ALDH1A1L3MBTL1POLBELANETDP1
SCHEMBL16108980 0.78 GAA (0.43) ALDH1A1L3MBTL1TDP1MAPTGAA
SCHEMBL14967125 0.76 ALDH1A1 (0.41) ALDH1A1L3MBTL1POLBELANETDP1
SCHEMBL14967009 0.76 FAAH (0.43) ALDH1A1POLBELANETDP1KDM4E
SCHEMBL14967432 0.76 ELANE (0.38) ALDH1A1POLBELANETDP1MAPT
SCHEMBL14967704 0.76 USP2 (0.40) ALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed