SCHEMBL14967009

SCHEMBL14967009

O=C(Oc1ccccc1)C1OC12CCCC2

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.43
TRPV1 Q8NER1 4/20 0.41
ALDH1A1 P00352 3/20 0.41
ELANE P08246 2/20 0.40
POLB P06746 2/20 0.40
KDM4E B2RXH2 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
RAB9A P51151 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
AKR1C1 Q04828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14966932 0.98 FAAH (0.45) FAAHTRPV1ALDH1A1ELANEPOLB
SCHEMBL14967125 0.97 ALDH1A1 (0.41) FAAHTRPV1ALDH1A1ELANEPOLB
SCHEMBL24111962 0.77 TSHR (0.45) ALDH1A1ELANEKMT2ATDP1
SCHEMBL14968010 0.77 ALDH1A1 (0.42) ALDH1A1ELANEPOLBKDM4ERAB9A
SCHEMBL14968285 0.76 ALDH1A1 (0.45) ALDH1A1ELANEPOLBKDM4ETDP1
SCHEMBL16109691 0.75 ALDH1A1 (0.41) ALDH1A1ELANEPOLBKDM4EHTT
SCHEMBL14967425 0.73 POLB (0.40) ALDH1A1ELANEPOLBRAB9A
SCHEMBL14967544 0.71 ALDH1A1 (0.41) ALDH1A1ELANEPOLBKDM4ERAB9A
SCHEMBL14967432 0.71 ELANE (0.38) ALDH1A1ELANEPOLBKDM4EHTT
SCHEMBL16110559 0.70 USP2 (0.39) ALDH1A1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed