SCHEMBL14967602

SCHEMBL14967602

CCOC(=O)C1(c2ccccc2)OC12CCCCC2

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 8/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
OPRD1 P41143 6/20 0.49
OPRK1 P41145 6/20 0.49
SLC22A1 O15245 2/20 0.49
SLC6A4 P31645 1/20 0.49
ADRA1A P35348 1/20 0.49
KCNH2 Q12809 1/20 0.49
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
PRCP P42785 1/20 0.43
SIGMAR1 Q99720 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16110026 0.99 OPRM1 (0.51) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL14968122 0.96 SMN1; SMN2 (0.55) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL14967001 0.89 PRCP (0.47) OPRM1SMN1; SMN2SLC22A1MEN1CYP1A2
SCHEMBL14968304 0.89 OPRM1 (0.48) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL14968336 0.88 PRCP (0.48) OPRM1SMN1; SMN2SLC22A1MEN1CYP1A2
SCHEMBL14967712 0.87 OPRM1 (0.49) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL14968095 0.87 ALDH1A1 (0.49) SLC22A1MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL14967771 0.86 ALDH1A1 (0.48) SLC22A1MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL14967662 0.85 LMNA (0.48) SMN1; SMN2SLC6A4MEN1CYP3A4CYP2C9
SCHEMBL14967839 0.85 ALDH1A1 (0.50) SLC22A1MEN1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed