SCHEMBL14968304

SCHEMBL14968304

CCOC(=O)C1(c2ccc(C)cc2)OC12CCCCC2

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 9/20 0.48
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
OPRD1 P41143 3/20 0.37
OPRK1 P41145 3/20 0.37
SLC22A1 O15245 1/20 0.37
SLC6A4 P31645 1/20 0.37
ADRA1A P35348 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967712 0.99 OPRM1 (0.49) OPRM1SMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL14967200 0.96 OPRM1 (0.49) OPRM1SMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL14967561 0.91 ALDH1A1 (0.41) OPRM1SMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL14967378 0.89 ALDH1A1 (0.42) OPRM1SMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL14967602 0.89 OPRM1 (0.50) OPRM1SMN1; SMN2MEN1KMT2AOPRD1
SCHEMBL14968056 0.89 KMT2A (0.42) OPRM1SMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL14967662 0.88 LMNA (0.48) SMN1; SMN2ALDH1A1MAPTMEN1LMNA
SCHEMBL14967811 0.87 MEN1 (0.39) OPRM1SMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL16110026 0.87 OPRM1 (0.51) OPRM1SMN1; SMN2MEN1KMT2AOPRD1
SCHEMBL14967644 0.87 KMT2A (0.43) OPRM1SMN1; SMN2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed