SCHEMBL1496842

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496858	0.95	MEN1 (0.41)	KMT2AALDH1A1MEN1LMNASMN1; SMN2
	SCHEMBL3233986	0.94	HDAC1 (0.42)	KMT2AMITFALDH1A1MEN1LMNA
	SCHEMBL1496864	0.92	ROCK2 (0.43)	KMT2AMITFLMNASMN1; SMN2ROCK2
	SCHEMBL11892993	0.89	ROCK2 (0.39)	KMT2AMITFROCK2PDCD1CD274
	SCHEMBL1496833	0.89	HDAC1 (0.38)	ROCK2PDCD1CD274HDAC1HDAC6
	SCHEMBL3224939	0.89	MEN1 (0.42)	KMT2AALDH1A1MEN1LMNASMN1; SMN2
	SCHEMBL1496977	0.89	ROCK2 (0.40)	KMT2AMITFSMN1; SMN2ROCK2HDAC1
	SCHEMBL1497001	0.88	TSHR (0.44)	KMT2AALDH1A1MEN1LMNASMN1; SMN2
	SCHEMBL1496905	0.88	ROCK2 (0.39)	ALDH1A1ROCK2PDCD1CD274HDAC1
	SCHEMBL1496834	0.88	ROCK2 (0.46)	LMNASMN1; SMN2ROCK2PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.