Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496990 | 0.98 | USP2 (0.37) | USP2MAPTTSHRHSD17B10OPRM1 | |
| SCHEMBL1497035 | 0.96 | ALDH1A1 (0.37) | USP2MAPTTSHRLMNAALDH1A1 | |
| SCHEMBL2386867 | 0.93 | HSD17B10 (0.38) | USP2MAPTTSHRHSD17B10OPRM1 | |
| SCHEMBL4228734 | 0.92 | HSD17B10 (0.37) | USP2MAPTTSHRHSD17B10OPRM1 | |
| SCHEMBL1496969 | 0.92 | AVPR1A (0.33) | USP2MAPTTSHROPRM1OPRD1 | |
| SCHEMBL4232503 | 0.91 | HSD17B10 (0.40) | USP2MAPTTSHRHSD17B10OPRM1 | |
| SCHEMBL1497024 | 0.91 | TSHR (0.37) | USP2MAPTTSHRHSD17B10OPRM1 | |
| SCHEMBL1496844 | 0.90 | USP2 (0.36) | USP2MAPTTSHRHSD17B10OPRM1 | |
| SCHEMBL1497027 | 0.90 | ALDH1A1 (0.31) | MAPTTSHRLMNAALDH1A1THRB | |
| SCHEMBL1497186 | 0.88 | HDAC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |