Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496969 | 0.96 | AVPR1A (0.33) | ALDH1A1GAALMNATHRBHDAC3 | |
| SCHEMBL1497035 | 0.94 | ALDH1A1 (0.37) | ALDH1A1GAALMNATHRBMAPK1 | |
| SCHEMBL4217911 | 0.92 | HDAC1 (0.35) | ALDH1A1GAALMNATHRBMAPK1 | |
| SCHEMBL1496990 | 0.90 | USP2 (0.37) | ALDH1A1GAALMNATHRBTSHR | |
| SCHEMBL10476411 | 0.90 | CSF1R (0.31) | — | |
| SCHEMBL1484238 | 0.90 | ROCK1 (0.32) | HDAC3HDAC2 | |
| SCHEMBL1496915 | 0.90 | USP2 (0.36) | ALDH1A1GAALMNATHRBMAPK1 | |
| SCHEMBL2386616 | 0.89 | HDAC1 (0.35) | ALDH1A1LMNAHDAC3HDAC2TSHR | |
| SCHEMBL1497186 | 0.88 | HDAC1 (0.33) | — | |
| SCHEMBL10476409 | 0.86 | TSHR (0.32) | ALDH1A1GAALMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |