SCHEMBL1496917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1497012	0.96	SIGMAR1 (0.42)	SIGMAR1HDAC1HDAC6ROCK2SUCNR1
	SCHEMBL1496919	0.95	SIGMAR1 (0.41)	SIGMAR1SUCNR1NAMPTDRD2HIF1A
	SCHEMBL8001525	0.94	POLB (0.42)	SIGMAR1ROCK2ROCK1NAMPTLMNA
	SCHEMBL1496941	0.91	SIGMAR1 (0.43)	SIGMAR1SUCNR1NAMPTDRD2ACKR3
	SCHEMBL3224387	0.90	SIGMAR1 (0.42)	SIGMAR1HDAC1SUCNR1NAMPTDRD2
	SCHEMBL1496985	0.90	USP2 (0.45)	SIGMAR1ROCK2NAMPTPOLBTSHR
	SCHEMBL1496867	0.89	USP2 (0.43)	SIGMAR1ROCK2NAMPTACHEPOLB
	SCHEMBL1496862	0.88	HTR5A (0.40)	HDAC1ROCK2ROCK1NAMPTHIF1A
	SCHEMBL8004861	0.87	USP2 (0.45)	SIGMAR1ROCK2NAMPTPOLBTSHR
	SCHEMBL1496892	0.87	CTSK (0.38)	HDAC1HDAC6ROCK1NAMPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.