SCHEMBL14970799

SCHEMBL14970799

OC1(c2ccc(Oc3ccc(C4(O)c5ccccc5-c5ccccc54)cc3)cc2)c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.49
THRB P10828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LTA4H P09960 3/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
OPRK1 P41145 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.37
GFER P55789 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
SLC6A3 Q01959 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22875765 0.96 PDK2 (0.54) PDK2THRBTDP1LTA4HNR1H2
SCHEMBL19038942 0.88 PDK2 (0.48) PDK2
SCHEMBL19039047 0.87 PDK2 (0.50) PDK2THRBTDP1KDM4EMEN1
SCHEMBL30281291 0.87 PDK2 (0.50) PDK2THRBTDP1KDM4EMEN1
SCHEMBL22875763 0.86 PDK2 (0.52) PDK2LTA4HNR1H2BAXMEN1
SCHEMBL7315127 0.85 PDK2 (0.51) PDK2MEN1MAPTOPRK1KMT2A
SCHEMBL22043560 0.83 PDK2 (0.47) PDK2
SCHEMBL17445906 0.82 PDK2 (0.49) PDK2
SCHEMBL31576206 0.81 PDK2 (0.45) PDK2THRBTDP1KDM4EMEN1
SCHEMBL14970800 0.81 PDK2 (0.45) PDK2THRBTDP1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203299-A1 RESIST UNDERLAYER FILM- FORMING COMPOSITION USING DIARYLMETHANE DERIVATIVE NISSAN CHEMICAL CORPORATION (JP) 2023-06-29 US disclosed
US-20230203299-A1 RESIST UNDERLAYER FILM- FORMING COMPOSITION USING DIARYLMETHANE DERIVATIVE NISSAN CHEMICAL CORPORATION (JP) 2023-06-29 US disclosed
US-11680133-B2 Material for forming organic film, patterning process, and polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-20 US disclosed
US-11680133-B2 Material for forming organic film, patterning process, and polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-20 US disclosed
WO-2021256527-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION USING DIARYLMETHANE DERIVATIVE 日産化学株式会社 2021-12-23 WO disclosed
US-20210388216-A1 Crosslinked Aromatic Polymer Compositions and Methods of Making Insulation Coatings For Use on Components Subject to High Temperature, Corrosive and/or High Voltage End Applications GREENE, TWEED TECHNOLOGIES, INC. 2021-12-16 US disclosed
EP-2909253-B1 CROSS-LINKED ORGANIC POLYMER COMPOSITIONS Delsper LP (US) 2021-11-10 EP disclosed
US-20210278766-A1 COATING-TYPE COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, POLYMER, AND METHOD FOR MANUFACTURING POLYMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-09-09 US disclosed
US-20210163675-A1 MATERIAL FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND POLYMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-03 US disclosed
US-10604618-B2 Compound, method for manufacturing the compound, and composition for forming organic film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-03-31 US disclosed
US-20140323668-A1 CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS GREENE, TWEED & CO. (US) 2014-10-30 US disclosed
US-20140316079-A1 Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications Delsper LP 2014-10-23 US disclosed
US-20140316079-A1 Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications Delsper LP 2014-10-23 US disclosed
US-20140284850-A1 Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability Delsper LP 2014-09-25 US disclosed
US-20140284850-A1 Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability Delsper LP 2014-09-25 US disclosed
WO-2014145834-A1 CROSS-LINKED ORGANIC POLYMERS FOR USE AS ELASTOMERS Delsper LP (US) 2014-09-18 WO disclosed
WO-2014066268-A9 CROSS-LINKED ORGANIC POLYMER COMPOSITIONS GREENE, TWEED OF DELAWARE, INC. (US) 2014-08-14 WO disclosed
US-20140213742-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP (US) 2014-07-31 US disclosed
US-20140213742-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP (US) 2014-07-31 US disclosed
WO-2013074120-A1 CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS GREENE, TWEED & CO. (US) 2013-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140284850-A1 Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability AOX1, DUOX2, HAO2 PDK2 890/4885THRB 4511/4885TDP1 2742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.