Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847520 | 0.71 | TUBB4A (0.56) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3847524 | 0.66 | FAAH (0.54) | MAPTKDM4EPKMCYP1A2CYP3A4 | |
| SCHEMBL5776970 | 0.64 | NAMPT (0.58) | MAPTCYP3A4TSHRSMN1; SMN2MAPK14 | |
| SCHEMBL5533097 | 0.64 | PDE4A (0.38) | MAPTKDM4EPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL5531063 | 0.63 | MEN1 (0.36) | MAPTKDM4EPKMSMN1; SMN2MDM2 | |
| SCHEMBL5773330 | 0.61 | MAPT (0.56) | MAPTKDM4EPKMS1PR3L3MBTL1 | |
| SCHEMBL8804947 | 0.60 | KDM4E (0.54) | MAPTKDM4EPKMCYP1A2CYP3A4 | |
| SCHEMBL8259936 | 0.60 | TSHR (0.62) | KDM4ECYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL10599026 | 0.60 | TSHR (0.70) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL832502 | 0.60 | NOD2 (0.57) | MAPTKDM4EPKMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-B1 | PARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INT (US) | 2013-05-29 | — | — | EP | claimed |